1.Backup your site
Before upgrading, if you can, backup your entire site. At a minimum,
backup your web.config.
Once you have backed up your web.config file, there are two ways you can use to extract
the “Install” version over your existing v3.x site.
2.Extract the Install.zip package over your existing version.
3. For DotNetNuke 4.x you must make sure that the Virtual Directory is configured for
.NET2.
4. In addition to the connection String setting under <appSettings> required in
3.x, 4.x also requires the same connection String to be set under the
<connectionStrings> section
<!-- Connection String for SQL Server 2005 Express -->
The work around is to go into admin>user accounts>user settings>and disabled Display Manage Services